- Product No.：894936
High quality cas 65277-42-1/Ketoconazole for Antifungal Treatment
Product Name Ketoconazole
CAS No. 65277-42-1
EINECS No. 265-667-4
Molecular Formula C26H28Cl2N4O4
Molecular Weight 531.43
Melting point 146°C
Appearance almost white crystalline powder
Standard Enterprise Standard
Packing 25KG/Drum or as per your requirements
Application medical use,Antifungal drugs.
3)Antiandrogenic and antiglucocorticoid
Ketoconazole (INN, USAN, BAN, JAN) is a synthetic imidazole antifungal drug used primarily to treat fungal infections. Ketoconazole is sold commercially as a tablet for oral administration (although this use has been discontinued in a number of countries), and in a variety of formulations for topical administration, such as creams (used to treat tinea; cutaneous candidiasis, including candidal paronychia; and pityriasis versicolor) and shampoos (used primarily to treat dandruff-seborrhoeic dermatitis of the scalp).
This product belongs to fluorinated triazole antifungal drug with the antifungal spectrum being similar as ketoconazole but antifungal activity being higher than ketoconazole. Its mechanism of action is through inhibition of essential component of the fungal cell membrane, the ergosterol biosynthesis enzyme, blocking the ergosterol synthesis and breaking the integrity of the fungal cell wall, further inhibiting their growth and reproduction. The product has potent antifungal activity against Candida albicans, Microsporum canis, Cryptococcus neoformans, histoplasma capsulatum and epidermophyton.
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